Silymarin and silybin are related milk thistle terms, but they do not name the same material. Silymarin is the extracted flavonolignan mixture that includes silybin, isosilybin,...

Silybin glucuronides and silybin sulfates are phase-II metabolites formed after the principal milk-thistle flavonolignan is absorbed. Glucuronidation uses UDP-glucuronosyltransferases to attach glucuronic acid, especially at the...

Silybin is the most abundant flavonolignan family in many silymarin extracts, while 2,3-dehydrosilybin is a more oxidized minor congener. Oxidation introduces a double bond between carbon...

Silybin and isosilybin belong to the flavonolignan mixture called silymarin, but their names describe different molecular arrangements. Silybin A and B together usually form the largest...